Fatehgarh Heritage Renaissance Resort in Udaipur uses wind and solar energyFew states of India are as evocative as Rajasthan–the very name conjures up images of medieval forts and flamboyant palaces, havelis and temples, castles on hilltops, picturesque villages and colourful fairs. Today, keeping with the times, Rajasthan’s heritage entrepreneurs are incorporating audio-tours, son et lumiore, alternative technologies for power generation or water harvesting. Nowhere is the change more apparent than in the cities of Udaipur, Jodhpur and Jaipur.Udaipur updateA cooking demonstration in progress at Deogarh MahalUdaipur has long been the epitome of Rajasthan’s romance since an island palace of the Maharanas was converted into the stunningly beautiful hotel with five-star trappings. One of the most exciting new heritage developments of Udaipur is Fatehgarh Heritage Renaissance Resort built from the remains of a demolished castle moved to the site from about 150 km away, supplemented with architectural fragments and doors from other heritage properties. Climb to the terrace and the glass-walled restaurant offers a breathtaking view of the lakes. There is much focus on eco and social conscious measures–an energy efficient design that makes the most of air movement and natural light, a wind turbine and solar panels that account for more than half the power consumption of the property, a water harvesting system inspired by medieval stepwell architecture, indigenous plantations to make a home for wildlife, local employment and a focus on using locally available materials. Vintage collections are still popular in the StateIf you are looking for a place to dine on a romantic night out, Udaipur is becoming known for those too–the Whistling Teal is a beautiful garden restaurant with a bar furnished with saddles and a coffee lounge; the park-like Ambrai has a view across the lake to the island palaces, the aptly named Sunset View Terrace in the City Palace complex, and the recently opened Raaj Bagh, which, as the name suggests, is done in colonial style with old dressers, antique furniture and vintage cars in a covered area.Like the properties, Udaipur’s shopping scene is also taking a modern twist–the Bougainvillaea Art Gallery showcases contemporary paintings, sculpture and artworks in aesthetically pleasing interiors with an ambience to match, Andraab is an attractive showroom recently opened for Kashmiri shawls and other handcrafted textile products, the trendy Ganesh Art Emporium, the Pristine Gallery, and galleries of individual artists.New entriesTraditional food is still popular in the StateAs you head up NH-8 from Udaipur towards Delhi, you come to one of Rajasthan’s most fairy-tale heritage hotels–Deogarh Mahal which rises from an elevation in the middle of a village with hill views from its terraces. The 50 rooms are imaginatively designed to match the character of the property. For something more exclusive, head for the owner’s four-suite Fort Seengh Sagar set amid shimmering waters. The decor is Rajasthani yet chic and minimalistic, with rooms having distinctive features–a fountain, a rockery, a temple, stone art and even a jacuzzi.Jodhpur jauntRamgarh Lodge near Jaipur is now a Gateway HotelStraight out of a storybook is Jodhpur’s Mehrangarh Fort, built in AD 1459. The new thing about the historical site is an audio-guided tour that will take you through the collections in the museum of princely memorabilia. At the end of the tour you come to the splendidly designed Museum Shop, which blends the fort’s old-world charm with contemporary visual merchandising to display art, artefacts, handicrafts, porcelain, jewellery, clothing and souvenirs. The display prompted an international magazine writer equalling the shop to being as good as an annexe of the New York’s Museum of Contemporary Art!Head from here to Raika Bagh and the Palace Road for Jodhpur’s superbly carpentered furniture, first-rate antique reproductions and handcrafted artefacts. There are some fun places to eat in this area–On-the-Rocks, as the name suggests, is a bar and restaurant in a rock garden along the imposing Ajit Bhawan Palace while Khaas Bagh has an arts and crafts gallery, a resort garden and a Bollywood themed dining area.A hidden gem in the city is MV Spice Shop in the Vegetable Market. The daughters of spice merchant, Mohanlal Verhomal, who was quite a legend among tourists, have come up with an extraordinarily innovative range of spice blends that they make at home from hand-ground spices. It is the place to buy anything from chai masala to a mutton curry mix.Jaipur goes contemporaryPolo tourism is catching up in the StateWhile Udaipur and Jodhpur remain old-worldly in their charm, Jaipur has burst out of its ‘Pink City’ shell with gleaming glass-and-steel shopping complexes, malls, supermarkets and multiplexes along its thoroughfare, Delhi-style plush new residential areas, and the ubiquitous CCDs, Baristas, fast food outlets and bars. But for visitors Jaipur is still about serious shopping. What is really exciting about shopping in Jaipur these days is the initiatives of the NGOs, cooperatives, self-help groups and artisanal families. A classic is Anokhi’s museum at the restored Chanwar Palkiwalon Ki haveli at Amber which won the UNESCO Asia-Pacific Heritage Conservation Award in 2000. Here you can watch craftsmen at work on block printing and woodcarving, learn about the history of block-printing besides experiencing the architecture of a haveli. It is just a few minutes away from Amber Fort, which now offers an audio-tour as well as a Sound and Light Show, with Gulzar’s words, Amitabh’s voice and music to match. Amber is also being given a makeover ahead of the forthcoming Commonwealth Games.The stylish showrooms of Anokhi and Fabindia in the city, the Soma on Jacob Road, the UN-supported Mojari which, as the name suggests, sells footwear from rural Rajasthan, and the blue pottery showroom called Kripal Kumbh, run by the daughters of the master ceramist Kripal Singh, are happening places to shop.Jaipur is also teeming with places to eat–from well-known names like Dasaprakash and Sankalp for South Indian food, Copper Chimney for North Indian, Little Italy, and so forth, to novel places like the Peacock Rooftop Restaurant or Om Tower Revolving Restaurant. Favourite evenings-out from Jaipur are village-theme restaurants like Chokhi Dhani, which also offers a range of folksy entertainments, an artisanal bazaar and camel and elephant rides.A couple of new options are also available for those who want to escape the city and yet not be too far from it. A good example of this is the Ramgarh Lodge, the former hunting lodge of the Maharajas of Jaipur, which is now a Gateway Hotel. And for a taste of something more energetic, get whisked away to Anokhi Farm outside Jaipur where you can learn the royal sport of polo. The training includes riding under supervision, stick-and-ball practice on wooden horses and practice chukkers.They say it’s just the beginning of modernisation. Let’s see what this year–the year of the Commonwealth Games in Delhi–spells for Rajasthan, its neighbour. advertisementadvertisement Fact fileFatehgarh–A Heritage Renaissance Resort Sisarma, Udaipur; tel: (0294) 241 3845Whistling Teal 103-Bhatiayani Chhohata, Udaipur; tel: 242 2067Ambrai Amet Haveli, Chandpole, Udaipur; tel: 243 1085Sunset View Terrace, City Palace Complex, UdaipurRaaj Bagh Fateh Sagar Lake, Udaipur; tel: 329 0228Bougainvillea Art Gallery Fatehsagar Lake, UdaipurAndraab New Fatehpura, Udaipur; tel: 242 3285Ganesh Art Emporium Jagdish Chowk, Udaipur; tel: 242 2864Pristine Gallery Bhattiyani Cohtta, Udaipur; tel: (0) 98291 84223Deogarh Mahal tel: (02904) 252 777; 253 333Fort Seengh Sagar Reservations through Deogarh MahalMehrangarh Fort Audio Tour Tel: (0291) 254 8790, 254 8992On-the-Rocks Circuit House Road, Jodhpur; tel: 251 0410Khaas Bagh Opp. Police Lines, Ratanada, Jodhpur; tel: 251 4513MV Spice Shop Clock Tower, Jodhpur; tel (0) 92520 00435;Anokhi Museum Amber Fort, Jaipur; tel: (0141) 253 0226Sound and Light Show at Amber Fort; 6.30 and 7.30p.m.Anokhi Jaipur; tel: 400 7244/45Fabindia MGF Mall, Jaipur; tel: 511 5997; Prithviraj Road; tel: 511 5992advertisementSoma 5 Jacob Road, Civil Lines, Jaipur; tel: 222 2778Mojari Vishwakarma Industrial Area, Jaipur; tel: 309 4260Kripal Kumbh Bani Park, Jaipur; tel: 220 1127Peacock Rooftop Restaurant Ajmer Road, Jaipur; tel: 237 3700Om Tower Revolving Restaurant MI Road, Jaipur; tel: 404 6666Chokhi Dhani Tonk Road, JaipurGateway Hotel Ramgarh Lodge One-hour drive from JaipurAnokhi Farm Tel: (01532) 275 0868
Hot on the heels of his Brit Award nomination, comes a new collaboration from chart-topping sound creator Naughty Boy: a brand-new PETA campaign that shows the Hotel Cabana producer reclining with his beloved cat, Naughty Bob, in his lap above the words “It’s Naughty Not to Neuter.”Naughty Boy’s PETA Ad“There’s no excuse for not neutering,” Naughty Boy says. “Animal shelters are severely crowded with dogs and cats, and that will continue as long as too many puppies and kittens are being born. We can fix the problem by ‘fixing’ our dogs and cats.”Why are Naughty Boy and PETA so fixated on getting animals fixed? One unspayed female cat and her offspring can produce 370,000 cats in just seven years, and an unneutered male can help create limitless litters of kittens. Every year in the UK, many thousands of unwanted animals are left at crowded animal shelters, where many must be put to death. The less fortunate ones will never make it to a shelter – they will be forced to fend for themselves in all weather extremes, lose battles with traffic and disease and have no constant food source. Fixing cats and dogs is also an easy way to ensure healthier, happier animals. Spaying females eliminates stressful heat periods and the risk of developing uterine infections, and it greatly reduces the risk of developing mammary cancer. Neutering makes males far less likely to roam or fight and prevents testicular cancer.Naughty Boy, also known as Shahid Khan, has worked with numerous musicians, including Chipmunk, Wiley, Leona Lewis, Jennifer Hudson, Cheryl Cole and Emeli Sandé. Hotel Cabana is his debut album, and its first single, “La La La,” featuring Sam Smith, reached the top of the UK’s music charts.Naughty Boy joins a growing list of musicians and producers – including Jay Sean, Waka Flocka Flame, Mark Ronson, Simon Cowell, Joss Stone, Paul McCartney and Morrissey – who have teamed up with PETA to promote kindness to animals.For more information, please visit PETA.org.uk.
Last month, the company said it would stop all non-essential spending on the expansion project to triple the amount of oil flowing from Alberta to the West Coast, which Alberta says is critical to reducing discounts on its product due mainly to pipeline bottlenecks.Kean reiterated that construction won’t be restarted unless there are sufficient assurances by the end of this month that it can proceed.Outside the meeting in downtown Calgary, about 50 vocal pipeline supporters armed with signs and slogans assembled on the sidewalk, chanting as passing cars honked their horns.Picketers Mike Owens and Derek B. Cooper say they were unimpressed with Morneau’s announcement, adding it offers further proof that the Liberal government has done too little to make sure the pipeline wins approval.Picket organizer James Robson of the Canada Action Coalition says the government shouldn’t have to offer money to make sure an approved pipeline will be built.(THE CANADIAN PRESS) CALGARY, A.B. – The CEO of Kinder Morgan Canada Ltd. says he “appreciates” an announcement by Finance Minister Bill Morneau that the government will compensate investors in the proposed Trans Mountain pipeline expansion if “unnecessary delays” cause costs to rise.Morneau says the government is willing to “provide indemnity” to any investors, be they the project’s original architects or otherwise, to ensure the controversial Alberta-B.C. project is able to proceed.Kinder Morgan chief executive Steven Kean offered no further comment during his remarks and declined to talk to reporters after his company’s first annual general meeting since being spun off by U.S.-based Kinder Morgan Inc. to hold most of its Canadian assets a year ago.
New Delhi: The government has deferred by one month the last date for bidding for the 14 oil and gas exploration blocks offered in the second round of Open Acreage Licensing Policy (OALP). Bids for the 14 blocks offered in OALP-II bid round, covering an area of 29,333 square kilometres, were to close Tuesday. “Bid submission closing date for OALP Bid Round-II stands extended up to April 10, 2019,” the Directorate General of Hydrocarbon (DGH) said in a brief notice. Also Read – Maruti cuts production for 8th straight month in SepIt did not give reasons for extending the deadline. The last date of bidding coincides with the bid deadline for the 23 oil and gas and coal-bed methane (CBM) blocks offered in the third round of OALP, which was launched on February 10. OALP-II bid round was delayed at six months and its launch came barely a month before the third round. Officials said OALP-II and OALP-III will run concurrently. Oil Minister Dharmendra Pradhan had at the time of launch of OALP-II bid round on January 7 stated that an investment of about Rs 40,000 crore is expected in the prospecting of oil and gas in blocks offered. Also Read – Ensure strict implementation on ban of import of e-cigarettes: revenue to CustomsIn the first round of OALP last year, as much as Rs 60,000 crore was committed in the exploration of oil and gas in 55 blocks or areas. In the third round, the government is expecting up to USD 700 million (about Rs 49,000 crore) of investment that it hopes will help raise domestic output and cut imports. India had in July 2017 allowed companies to carve out blocks of their choice with a view to bringing about 2.8 million sq km of unexplored area in the country under exploration. Under this policy, called open acreage licensing policy or OALP, companies are allowed to put in an expression of interest (EoI) for prospecting of oil and gas in any area that is presently not under any production or exploration licence. The EoIs can be put in at any time of the year but they are accumulated twice annually. The blocks or areas that receive EoIs at the end of a cycle are put up for auction with the originator or the firm that originally selected the area getting a 5-mark advantage. The two window of accumulating EoIs end on May 15 and November 15 every year. EoIs accumulated till May 15 are supposed to be put on auction by June 30 and those in the second window by December 31. The first OALP round was launched in 2017 and bids came in by May 2018. EoIs for second round closed on May 15, 2018, and the blocks were supposed to be put for auction by June but the round was for reasons unknown delayed. OALP-II was finally launched on January 7. In the meanwhile, EoIs in the third window also closed on November 15, 2018 with as many as 18 blocks and five CBM blocks, measuring 31,722 sq km, being sought for. OALP-III bid round was launched on February 10 with April 10 as the last date for bidding. Officials said the 14 blocks in OALP-II are estimated to hold in-place resource of 12,609 million tonne oil and oil equivalent gas. In OALP-1, mining mogul Anil Agarwal-led Vedanta Ltd walked away with 41 out of 55 blocks bid out. State-owned Oil India Ltd won nine blocks while Oil and Natural Gas Corp (ONGC) managed to win just two. State gas utility GAIL, upstream arm of Bharat Petroleum Corp Ltd (BPCL) and Hindustan Oil Exploration Co (HOEC) won one block each. The 55 blocks have a total area of 59,282 sq km. This compares to about 1,02,000 sq km being under exploration prior to OALP. Blocks are awarded to the company which offers the highest share of oil and gas to the government as well as commits to doing maximum exploration work by way of shooting 2D and 3D seismic survey and drilling exploration wells. Increased exploration will lead to more oil and gas production, helping the world’s third largest oil importer to cut import dependence. Prime Minister Narendra Modi has set a target of cutting oil import bill by 10 per cent to 67 per cent by 2022 and to half by 2030. Import dependence has increased since 2015 when Modi had set the target. India currently imports 83 per cent of its oil needs. The new policy replaced the old system of government carving out areas and bidding them out. It guarantees marketing and pricing freedom and moves away from production sharing model of previous rounds to a revenue-sharing model, where companies offering the maximum share of oil and gas to the government are awarded the block. The government prior to this had been selecting and demarcating areas it feels can be offered for bidding in an exploration licensing round. Under this, 256 blocks had been offered for exploration and production since 2000. The last bid round happened in 2010. Of these, 254 blocks were awarded. But as many as 156 have already been relinquished due to poor prospect.
Tehran: Iran’s foreign ministry warned the UK on Tuesday that giving diplomatic protection to a British-Iranian mother jailed in Tehran would not make the situation “easier”, state news agency IRNA reported. Britain on Friday extended the status to Nazanin Zaghari-Ratcliffe, who was arrested in Tehran in 2016. “What is certain is that the British government’s move lacks goodwill and is in no way constructive or positive,” said ministry spokesman Bahram Ghasemi on Tuesday. Also Read – Imran Khan arrives in China, to meet Prez Xi Jinping”If it does not make the situation more complicated, it will surely not make things easier.” Zaghari-Ratcliffe, who worked for the Thomson Reuters Foundation — the media organisation’s philanthropic arm — is serving a five-year jail sentence for sedition. She has denied all the charges against her. Diplomatic protection is a rarely-used mechanism allowing governments to seek protection for their citizens on the grounds that they have been wronged by another state. Also Read – US blacklists 28 Chinese entities over abuses in XinjiangBritain’s Foreign Secretary Jeremy Hunt said Friday that London would take the “extremely unusual” step of extending diplomatic protection to the jailed mother. This would signify the “formal recognition by the British government that her treatment fails to meet Iran’s obligations under international law”, he said. But Ghasemi denied this, saying Zaghari-Ratcliffe is “enjoying all legal and citizenship rights — both throughout her trial proceedings and during the conviction period”, including medical care. Tehran was informed of the UK’s decision via official channels, and is currently studying the legal and political implications, the spokesman said. Ghasemi dismissed the move as “merely reflecting a political decision by the UK” and said that it would not “in itself bring about a new legal status internally or internationally.” Iran’s envoy to London said last week that the UK’s decision “contravenes international law”, as governments can only exercise such protection for their own nationals. Writing on Twitter, Hamid Baeidinejad said Iran does not recognise dual nationality. “Irrespective of UK residency, MS Zaghari thus remains Iranian,” he wrote.
Tezpur (Assam): A Muslim man was allegedly beaten up and forced to eat pork by a group of people who were angry over his selling beef in Assam, police said Tuesday. Consumption of pork is a taboo among most Muslims.The victim, Shaukat Ali (48), was assaulted by a group of locals at Madhupur weekly market in Biswanath district on Sunday and required hospitalisation, Superintendent of Police Rakesh Raushan said. A video of the incident that has gone viral showed a dazed Ali surrounded by some people who angrily demanded to know from him where he came from and whether his name figured in the contentious National Register of Citizens that intends to weed out illegal migrants. Also Read – India gets first tranche of Swiss bank a/c detailsAli, according to Raushan, was beaten up by locals not aligned to any fundamentalist organisation. Ali, who owns a food stall, claimed he was force-fed pork by the assailants, but police did not confirm it. “We have also heard about that. It is a matter of investigation. It is only after that has been done that I will be able to tell,” the SP said. A man was arrested in connection with the incident and questioned. Ali claimed he had been selling beef at the market for over three decades and never faced such a situation. Also Read – Tourists to be allowed in J&K from ThursdayThe group also beat up 42-year-old Kamal Thapa, the contractor of the market, for allowing Ali to sell beef dishes. Cow slaughter and consumption of beef is not banned in the state but the Assam Cattle Preservation Act, 1950, permits the slaughter of only cattle above 14 years of age after due certification by a veterinary officer. The Sunday’s incident came to light when a video shot by one among the group of assailants went viral on social media. A case was registered with the Biswanath Chariali police station on the complaint of the victim’s brother Sahabuddin Ali on Monday evening.
Japan is working toward restoring Australian visitor numbers in 2012 after a fall in figures last year as a result of the earthquake and tsunami tragedies. Australian Consul-General of Japan Masahiro Kohara spoke to up to 130 delegates attending the Japan Snow & Adventure Seminar 2012 at the Four Points by Sheraton Sydney last night about the region’s plans to stimulate travel from down under. “The motivation for this expo is to provide the Australian market with up-to-date information and the confidence to sell Japan snow products,” he said. Japan National Tourist Organisation (JNTO) Viara Yanatchkova said Australian visitor numbers were on the rise with the first two months of this year recording growth in arrivals. “There was a 30 percent decrease in the number of Australian tourists in 2011 but with the help of last minute bookings, January and February 2012 saw an influx of 40,132 Australian visitors to Japan.” Ms Yanatchkova highlighted Japan’s accessibility as one of the key reasons Australians should visit. “There are no visa requirements for Australian visitors, the time difference is minimal so there’s little to no jet lag and Japan Airlines, Qantas and Jetstar all fly direct routes between Australia and Japan,” she said. The Qantas subsidiary is also making it easier to travel throughout Japan domestically, launching Jetstar Japan later this year. Speakers from various ski resorts across Japan made presentations at the Seminar, emphasising the quality of the product on offer and why it would be attractive to Australians. “Australians love a ski village, the lifestyle, the vibe. Over here, we have it,” a representative from the Niseko resort said. Scott Tovey from New Furano Prince Hotel said “consistency, affordability, interlinked resorts and uncrowded slopes” were just a few of the advantages of travelling to Japan for a snow or adventure holiday. The 2012 Seminar was held in Melbourne on 21 May at Rydges Melbourne Hotel. Source = e-Travel Blackboard: P.T
The Australian Tourism Data Warehouse (ATDW) and V3 have agreed to continue Australia’s unique national booking exchange platform, TXA.This news pleases over 7,000 tourism industry suppliers as they are reliant on Tourism Exchange Australia (TXA) as part of their distribution strategy.The continuation of TXA will ensure distributors and operators can continue to increase their online exposure and sales and provide consumers with the ability to source high quality, live tourism content and information and book, securely pay and instantly confirm online.ATDW formed a partnership with V3 in 2008 to deliver an inclusive national open, booking platform branded, TXA, which combines ATDW’s database with V3’s Open Booking Exchange (OBX) technology.ATDW chief executive officer Liz Ward, said that the extension of this alliance provides the technology support for TXA and ATDW provides the quality product content.“With so many tourism operators using TXA as part of their distribution strategy and many distributors reliant on TXA for access to a broad cross section of Australian tourism product, we are both very pleased to continue to provide TXA. It will be business as usual with no disruption to businesses connected to TXA,” Ms Ward said. Source = ETB Travel News: Lewis Wiseman
Related7+ Seater Car and MPV HireWhy hire a 7, 8 or 9 seater car? Large MPVs and 7+ seater cars are a great option for family or group holidays if you’re planning to do a lot of traveling. The additional seating and spacious cabins ensure that all your passengers have plenty of space with room…7+ Seater Car and MPV Hire in MalagaPopular Car Hire Locations Near Malaga 7+ Seater Car Hire from Malaga Airport 7+ Seater Car Hire from Gibraltar Airport How to search for 7+ seater cars to hire in Malaga on Skyscanner Using the search box above, or on our Malaga car hire page, select your pick-up location as…7+ Seater Car and MPV Hire in DublinPopular Car Hire Locations Near Dublin 7+ Seater Car Hire from Dublin Airport How to search for 7+ seater cars to hire in Dublin on Skyscanner Using the search box above, or on our Dublin car hire page, select your pick-up location as well as the pick-up and drop-off dates… At a certain size, minivans start to look less like a car/van hybrid and more like a small bus. Indeed, large minivans are essentially commercial vans you’d typically see being driven by tradesmen or being used to transport goods, but in this case outfitted with multiple rows of seats to accommodate up to 9 passengers and all their luggage and usually much more luxuriously equipped. Often used as executive shuttle busses by hotels, these can also be hired from rental companies for personal use if you are travelling with a large group or just have a lot of luggage and equipment to transport. Examples of vehicles in this class include: MPV (aka Minivan, Multi-purpose vehicle, people carrier) Popular Car Hire Locations Near Orlando SUVs are a common site on roads all over the world now – large vehicles usually with ample ground clearance giving them an off-road look (although they are not always 4wd and not always suitable for offroading!) providing practical space, high driving position and plenty of seating. The larger vehicles in this category can comfortably seat 7 with reasonable luggage space left over. 7 seaters in this category include: Mercedes E-Class EstatePeugeot 308 SWAudi A6 Avant 7+ Seater Car Hire from Orlando International Airport Volvo XC90Peugeot 5008Nissan X-TrailKia SorentoLand Rover Discovery 7+ Seater Car Hire from Orlando Sanford Airport There are several different types of 7+ seater cars and, depending on where you are hiring from, one or more of the following types may be available: These are probably the most common type of 7+ seater family car available today. Essentially a van shaped car with three rows of seats and typically with sliding rear doors providing easy access to the two back rows of seats. Examples of cars in this class include: Using the search box above, or on our Orlando car hire page, select your pick-up location as well as the pick-up and drop-off dates and times then hit Search ->When the results have loaded, select 7+ from the Passengers filters in the Filter menu.Choose a preferred pickup location from the map or the list to see the selection of 7+ seater cars available to hire from that location.When you find one that suits your needs, click on the Select button to be shown price options from different suppliers and see more detail about the rental options.When you find one you would like to book, click on Select next to that option to be taken to the site where you can reserve the vehicle. Large estate cars with 7+ seats are less common to find these days, having mostly been replaced by MPVs and SUVs, but some are still around and may be available depending on where you are renting your car from. Estate cars are often extended versions of hatchbacks or saloons, creating additional boot space and, in some cases also allowing an extra row of seats, whilst still being a low to the ground car. These are often known as 5+2 seat cars as they usually don’t have a proper back row of seats and instead just have 2 extra seats which fold out from the floor of the boot. This of course may mean sacrificing luggage space if you want to use one of these to carry 7 people. Examples of cars in the class include: How to search for 7+ seater cars to hire in Orlando on Skyscanner SEAT AlhambraVolkswagen SharanFord GalaxyChrysler Grand VoyagerMercedes-Benz V-Class SUVs (aka 4x4s, Sports Utility Vehicles) Pick-up LocationPick-up DateTime00:0000:3001:0001:3002:0002:3003:0003:3004:0004:3005:0005:3006:0006:3007:0007:3008:0008:3009:0009:3010:0010:3011:0011:3012:0012:3013:0013:3014:0014:3015:0015:3016:0016:3017:0017:3018:0018:3019:0019:3020:0020:3021:0021:3022:0022:3023:0023:30Drop-off DateTime00:0000:3001:0001:3002:0002:3003:0003:3004:0004:3005:0005:3006:0006:3007:0007:3008:0008:3009:0009:3010:0010:3011:0011:3012:0012:3013:0013:3014:0014:3015:0015:3016:0016:3017:0017:3018:0018:3019:0019:3020:0020:3021:0021:3022:0022:3023:0023:30Return car to a different locationDriver aged between 25 – 75Search Estate Cars Volkswagon Transporter ShuttleMercedes Vito TravelinerFord Transit 9 SeaterPeugeot Traveller Large Minivan Types of 7+ Seater Vehicles to Hire in Orlando
Categories: Steven Johnson News Each Fourth of July, we celebrate America’s Declaration of Independence as we commemorate the anniversary of our country’s founding. This spirit of independence is something we should cherish and must preserve for our children.Just as our government is not beholden or dependent on another government for its sovereignty, we as individuals should not rely on federal, state and local governance. Our founding fathers envisioned a nation where citizens could pursue their dreams, seek their own happiness and accomplish their own goals, objectives and aspirations aside from government intrusion in their lives and interference in the marketplace.What they did not envision was a country of individuals dependent on government for their well-being. They did not envision a country of businesses lobbying state and federal governments for special privileges and immunities.Our founding fathers believed in the principles of freedom, entrepreneurship, individualism and independence. They believed the role of government in our lives should be very limited. The Constitution mandates that Congress shall meet “at least once in every year.” Our founding fathers would be astounded if they saw the extent government plays in our lives today.In honor of everything our founding fathers accomplished and stood for, I believe we should take a step back and look at where our country is today. What do we do right? What do we do wrong? What could we do better?How can we as a society ensure that our children grow up and live in a country more free, more prosperous and more independent than the one we live in today? We have been afforded great opportunities, with many things that are good and right in our nation but it seems that there are some areas of improvement that can be made. One of the biggest changes is demanding government take a step back, not be so involved in our lives and simply let us interact with our neighbors as we see fit. Government does not give us our freedom and independence, it is there to preserve and protect them.Unfortunately, we have a mindset of ‘ask not what you can do for your country, but what your country can do for you.’ Let’s change that mindset to what President John F. Kennedy envisioned, let’s be that free and independent country, let’s be a sovereign country, let’s demand freedom and equality in opportunity, let’s oppose corporate welfare and special handouts, and most importantly, let’s fight for independence! 29Jun Declaration of Independence op-ed
Ukrainian telco and IPTV provider Ukrtelecom has been bought out by SCM Group, which is owned by Ukrainian billionaire Rinat Akhmetov. “The SCM Group will become the owner of UA Telecominvest Limited and will receive control over a 92.79% stake in public joint-stock company Ukrtelecom, after obtaining all the required permits, including ones from the antimonopoly agencies,” the firm said in a statement, published by national news agency Interfax Ukraine.The stake was bought from Austrian investment group EPIC, which acquired it from the Ukranian government in 2011 when Ukrtelecom was privatised. The new deal was done for undisclosed terms.
3D channel 3net will develop a library of content it can distribute in multiple formats including 4K 3D and HD 3D, but does not currently have plans to launch a dedicated 4K channel, according to CEO Tom Cosgrove.Speaking to DTVE at IBC, Cosgrove said that the amount of content being shot in 4K is growing, even if the version that is finally distributed is not in 4K. Cosgrove said he expected “services to roll out by this time next year and TVs priced at under $2,000 [to be available]”. He said he expected 4K to ultimately achieve widespread take up by consumers, unlike 3D which has remained a minority taste. “3D was a choice – some people love and some do not love it. No-one is not going to love 4K,” he said.Cosgrove said that 3net would look to develop HD 3D programmes as well as 4K content. He said 3net Studios had already produced 4K series Space: Unravelling the Universe and Flight and would seek to build a library fo content that could be distributed as HD 3D shows. However, he said there are no current plans to launch a dedicated 4K channel. “It’s a little too soon for a 4K channel,” he said. “We are looking into things, but one issue you will have is there are limits on rights. We are coming in with content where rights are available globally.”Cosgrove said that “over time we will build up a healthy library in 4K” and that it is possible that the channel would “create a branded destination – whether linear or non-linear” for 4K in the future.
ShareTweet Santa switches on Derry’s Christmas lights with the help of Mayor Cllr Brenda Stevenson and MC, Mark Patterson, BBC Radio Foyle.Over 10,000 people packed to Derry city centre last night to welcome Santa for the Christmas lights switch on, marking the beginning of the city’s Festive Time programme.Mayor of Derry Brenda Stevenson joined Santa on stage in the Guildhall Square after he swooped in specially from the North Pole, landing on the city’s historic walls.After a bit of “hide and seek” fun and switching on the illuminations, he delighted the thousands of children by distributing sweets. SANTA LIGHTS UP DERRY FOR CHRISTMAS was last modified: November 21st, 2014 by stephenstephen Tags: Speaking after the event. Derry Mayor Cllr Brenda Stevenson said: “I was absolutely thrilled to see so many young families out this evening to see the switch on – and meeting Santa was just the icing on the cake.“Looking out at the sea of smiling faces, all there to welcome Santa, was just fantastic and it’s really put me in the festive spirit. And this is just the beginning of the Christmas fun!”Meanwhile, the Christmas Village will open at Ebrington Square on 28 November featuring the LegenDerry Ice Rink, Festive Funfair and pop up cinema. christmasDerrylightsSanta
We see the potential in gold equities, as we believe the price of gold is going higher, but big investors with billions of dollars to pour into an market don’t. Their money, for the most part, is still on the sidelines. This phenomenon leads us to predict that someday these institutional investors will enter this sector en masse. Once the facts sink in and the institutional world becomes convinced gold and silver prices will maintain a sustainable uptrend, they’ll be much more attracted to the equities – and just as stubborn about changing their minds once they’re on board. Now, it’s possible this group may have to be beat over the head by relentlessly rising precious-metals prices before they enter the industry. They’ll have to believe that, say, gold hitting $1,900 again isn’t a temporary fluke but a sustainable uptrend. I don’t know what price the metal would have to maintain or how long it would have to stay there before they jump on board, but given the above chart, I think it’s safe to say they won’t be the first to the party. I personally think it will be something along the lines of what we outlined in the recent Hard Assets Alliance letter. Whenever and however it happens, though, the stampede from institutional investors into this tiny industry will be sudden and dramatic, because they tend to have a herd mentality. No one wants to be left behind. Just like they don’t want to risk buying something all their colleagues are ignoring now, they’ll rush to own the popular and exciting investment when gold stocks have their day. The consequence of this will result in dramatically higher stock prices. How high? Well, this group loves to use price models, and fair value for Newmont Mining (NEM), based on its Reserves, would be about $200/share (it’s currently trading around $44). And that’s at $1,700 gold – as the spot price rises, the value of NEM will rise exponentially, since gold would be rising faster than costs, even when inflation kicks in. That is why I’m excited about the producers. It’s the first place the institutional world will turn when gold makes a sustained move higher. Come the day those investors believe gold is about to become part of the monetary system, that bonds are no longer a safe place for money, that inflation is about to get out of control, or whatever it might be that changes their paradigm, they’ll flood into our little market and push share prices higher by an order of magnitude. When this shift gets under way, we’ll already own the stocks that institutional investors will be clamoring to buy. Maybe we should thank them now. Bank and brokerage analysts know their products, too. But when it comes to helping you make an informed decision about where the gold market is headed, they have, as Rick Rule is fond of saying, a record unblemished by success. Every year major banks and brokerage houses provide their four-year forecasts for the gold price. The following chart documents the average price projection of 25 top analysts over the past seven years, many of whom specialize in the resource industry. I might suggest pushing away from your desk so that when your jaw drops it doesn’t hit the keyboard. Common sense dictates that when you need information or advice on something you’re unfamiliar with, you consult with a professional. That’s what people do, whether refinancing a home, choosing an insurance product, or fixing a broken heater. While professionals certainly have their own agendas, they still know more about their products or services than others, and can at least help them make more informed decisions. If institutional investors are largely absent from this market, why is gold rising every year? Gold is not a trading sardine for institutions. Gold is supported by strong physical demand from individuals around the world and from central banks. Read our take here. You can see that every year since 2007, bank and brokerage analysts have as a group predicted that gold would fall, sometimes dramatically, over the next four-year period. For example, in 2007 the consensus of all estimates was that gold would decline from $656 to $523 by 2011. Instead, the price rose 140% to an average of $1,572 that year. Similarly, they predict this year that gold will fall from $1,665 to $1,515 by 2017. Even if they thought gold would move higher the first year, their best guess was that it was ultimately headed lower. So far they’ve been wrong every time. For the most part, these are analysts who do nothing but study the resource markets all day long. It’s their job. No one gets it right all the time, but this kind of track record is embarrassing. The obvious lesson is for investors to ignore price predictions from the major banks and brokerage houses – they just don’t get it. I’m sure most readers of this publication already know that. However, there’s a much bigger implication of this data that may not immediately come to mind… Why would I as a fund manager or institutional investor buy a gold stock if my analysts tell me the price of gold is going to fall? Answer: I wouldn’t. If the price of the product a company sells is expected to decline over the next few years, would you buy the company’s stock? Its earnings are almost certain to fall. As a manager of millions (or billions) of dollars, you wouldn’t buy any investment with this kind of outlook. There’s more. These same banks and brokerages have also been predicting the price of oil will rise (almost) every year. While they’ve occasionally been right about that, it means that margins for the gold producers would be expected to fall, since roughly 10% of their costs are related to fuel. So again… Why would I as a fund manager or institutional investor buy a gold stock if my analysts tell me profit margins are expected to fall? Answer: I wouldn’t. It doesn’t matter that analysts have been consistently wrong. What matters is that if the institutional world believes the gold price is likely decline and/or that margins are likely to fall, they’re not going to stick their necks out and buy gold stocks. They could lose their bonuses or even their jobs if their analyst’s predictions came true and they’d bet against them. This could be the explanation for why hedge funds, institutional investors, and other large investors haven’t entered this market en masse and could account for the disconnect between the price of gold and the trajectory of gold stocks.
Free demo here The Turkish lira is in free fall… Two weeks ago, it announced a series of measures that it hopes will bring liquidity and support the country’s banking system. (You can read more details on these measures in this Dispatch.)Turkish President Recep Tayyip Erdoğan also asked Turkish people to get rid of their U.S. dollars and euros:If there are dollars under your pillow, take these out… immediately give these to the banks and convert to Turkish lira and, by doing this, we fight this war of independence and the future.In other words, Erdoğan wanted Turks to sell dollars to keep the lira from plunging.But many people did the exact opposite. In fact, my Turkish friend told me—at the height of the lira’s sell-off—that “all her friends were exchanging lira for dollars.”But that’s not all they were buying. I know because I was just in Turkey… We know this because trading volumes on major Turkish crypto exchanges surged during the lira’s recent crash.According to CoinMarketCap, trading volumes on BTCTurk soared 131% when the lira was falling. Paribu, another Turkish crypto exchange, saw a 108% spike in trading volume.This tells us many Turkish people took shelter in bitcoin and other cryptos. But that shouldn’t come as a surprise. I spent about three weeks in Istanbul. I also visited Turkey’s gorgeous southern coast.That was enough time for me to truly experience Turkey’s currency crisis.You see, one dollar was worth about 4.8 lira when I showed up in Turkey. Three weeks later, one dollar was worth 7 lira.This means that the lira’s value plunged 31% against the dollar in less than a month. Put another way, the dollar strengthened 46% against the lira over the same period.Now, I didn’t mind this as a tourist. Everything from meals to cab rides got cheaper by the day.But the lira’s plunge hammered everyday Turkish people, like my friend. Things got so bad that the Turkish central bank stepped in… “I don’t buy anything from Amazon anymore. I buy everything from AliExpress now. It takes two months to get here, but I save about $1.”My friend Canset told me this recently. Now, you might be wondering why she’s using AliExpress—an online retail service based in China—to purchase her everyday items.She’s doing this because the money in her wallet is losing value rapidly.You see, my friend lives in Turkey, which is in the middle of a currency crisis.Of course, you’d already know that if you have been reading the Dispatch. I wrote about the situation here and here. It’s a major story we’re following closely—and it’s another reason why you should bet on cryptocurrencies today.I’ll explain why in a moment, but first let me recap what’s happening in Turkey. Of course, Turkey isn’t the only country where desperate people have turned to bitcoin… Just click here Recommended Link Turks have been embracing cryptocurrencies for years… In fact, the market research firm Ipsos recently conducted a survey on crypto ownership across 15 countries. And it found that 18% of Turks own some form of cryptocurrency. That’s double the European average of 9%.That’s impressive. But crypto ownership in Turkey should keep rising.I say that because the same survey found that 53% of Turks believe digital currencies will be the dominant online payment method in the future. And 51% expect the value of cryptocurrencies to rise over the next year.This is a big deal. Many Turks also loaded up on cryptocurrencies… This year the lira has fallen 38% against the dollar. That’s a staggering decline. Only the Venezuelan bolívar and Sudanese pound have fared worse this year.This is why my friend is changing how she shops. If she doesn’t, she could run out of money.She’s certainly not alone, either.People all over Turkey are under pressure. You can almost feel the tension in the air. It tells me more Turks will take refuge in cryptos if the lira keeps falling… — So consider speculating on cryptos if you haven’t yet. Bitcoin is a good place to start.Just remember that bitcoin and other cryptos are extremely volatile. As always, never bet more money than you can afford to lose. And you should use stop losses and take profits as they come. Regards,Justin SpittlerBudapest, HungaryAugust 27, 2018Reader MailbagToday, we see that not everyone agrees with Doug Casey’s take on the Alex Jones ban…Doug, you have gotten completely off topic with Alex Jones. All you say, and others as well, about Jones’ content and his delivery is correct. But ask yourself this question: How did this cabal all of a sudden come together? All of a sudden the technocrats and the media in unison attacked Jones. Feel sorry for Jones… NOT! As of Monday, he was the No. 1 news app. CNN, who had held that title for years, was destroyed. Why? Because you and the public jumped on his band wagon. Jones is a gate keeper for the Israeli agenda… and where did you get this that he was somehow a 9/11 truther?You need to re-examine your information, Mr. Casey. He argues all of the time whether the narrative was wrong and Israel was a haymaker of this false flag agenda. This was not to destroy Jones, as you and others portend. It was to drive the insouciant to his site to take the alt net to its extreme. Please take a different look to see what he has been and still is. You are as dead wrong as all who have fallen for the scam of the century. —RichardAs always, if you have any questions or suggestions for the Dispatch, send them to us right here.In Case You Missed It…Have you seen these strange-looking metal poles in your city? Most people have no idea what they’re for. But in just a few short years, these towers could completely upend the entire $479 billion smartphone industry… and make well-positioned investors rich. But together they could light a serious fire under the bitcoin price. It’s also possible that bitcoin (or some other crypto) could emerge as a medium of exchange in one of these places. That would let the world know that cryptos aren’t just another speculative vehicle. They’re a legitimate threat to paper money. Relative to the dollar, the Venezuela bolívar has lost 99.99% of its value this year. The Argentine peso is down 40% on the year. The South African rand is down 12%. These are enormous declines. They’re the kind that push people to take shelter in bitcoin. NASDAQ calls it: “The biggest investment opportunity in years.” The Smart Phone Killer1000x faster, 1000x more capacity, plus the power to download a 2-and-a-half hour movie in one second. Get positioned by October 1, and you could pocket a sweet $150k profit. Of course, skeptics will be quick to point out that bitcoin hasn’t been a good store of value this year.It’s down 52% on the year versus the lira’s 38% decline. Not only that, many lesser-known cryptos are down 80% or more this year.I won’t dispute those numbers. But let’s not forget that cryptos are coming off an incredible rally.The bitcoin chart below says it all.You can see that bitcoin’s still up 2,874% over the past three years. And yes, that includes its recent crash.You’ve also got to remember that bitcoin’s been here before. You see, bitcoin has crashed 30% or more 11 other times since 2010. Each time, it bounced back stronger.You can’t say the same about the lira, which has been in steady decline. In fact, it’s lost 70% of its value against the dollar since the start of 2013. — Recommended Link Now, I’m not saying any of these countries could push bitcoin to new highs on their own… That would obviously be extremely bullish for the crypto market… President Trump Gives Order to Locate New Type of FuelRecently, President Trump signed an executive order that mandates the Interior Department to begin mapping the country to locate America’s “Brandt Oil” reserves.“Brandt Oil” is a new, clean super fuel that’s so powerful, less than two gallons worth contains enough raw energy to power your house for nine years. So it’s no surprise “Brandt Oil” applications are going mainstream.And just like any new energy revolution, early investors are minting millions. Already we’re seeing investors bag rare gains as high as 2,343%, 3,750%, and even 4,628%.To get the full story on exactly what “Brandt Oil” is – and why it’s making investors so much money right now…
Every week in Murfreesboro, Tenn., Zibin Guo guides veterans in wheelchairs through slow-motion tai chi poses as a Bluetooth speaker plays soothing instrumental music.”Cloudy hands to the right, cloudy hands to the left,” he tells them. “Now we’re going to open your arms, grab the wheels and 180-degree turn.”The participants swivel about-face and continue to the next pose. Guo, a medical anthropologist at the University of Tennessee at Chattanooga, has modified his tai chi to work from a seated position. Even though many of the participants are not wheelchair-bound, using the mobile chairs makes it easier for them to get through a half-hour of movement.The U.S. Department of Veterans Affairs has given $120,000 in grant money to Guo to spread his special wheelchair tai chi curriculum. He started in Chattanooga, and has expanded his class offerings to Murfreesboro.This idea of going beyond prescriptions — and especially beyond opioids — in dealing with different sorts of pain and trauma has become a focus of the VA nationally.In Tennessee, nearly a quarter of all VA patients with an active medical prescription were on opioids in 2012. That number is now down to 15 percent, but that’s still higher than in most other parts of the country.According to a national survey from 2015, nearly every VA hospital now offers some kind of alternative health treatment — like yoga, mindfulness and art therapy.Guo is teaching people in a half dozen VA hospitals in Florida, Texas, Utah and Arizona to use his version of tai chi. He believes the focus on breathing and mindfulness — paired with manageable physical activity — can help ease a variety of ailments.”When you have a good amount of body harmony, people tend to engage in proactive life,” he says, “so that helps with all kinds of symptoms.”In addition to making a vet feel better physically, the VA also hopes these alternative therapies might help ease symptoms of conditions like post-traumatic stress disorder.Thomas Sales, of Nashville, Tenn., says his latest panic attack caught him by surprise. “Night before last, when we had the thunderstorm,” he says. “The thunder is a big trigger for some people.”It’s been 25 years after Sales fought in the first Gulf War with the Navy Special Warfare Command, and he still has panic attacks regularly.”You’ll find yourself flashing back to being out there with the fellas, and you’ll just kind of snap,” he says. “And I found myself, for some reason, thinking about doing the breathing techniques [from tai chi], and doing the ‘heaven and earth,’ and then breathing deep and slow.”Sales says he knows it must look crazy to some people when he reaches to the sky and then sweeps his arms to the ground. There was a time when he would have agreed. Most of the patients in this class had some skepticism going into the tai chi program. But Vietnam veteran Jim Berry of Spring Hill, Tenn., says he’s now convinced of its value.”My daughter sent me a t-shirt that sums it up,” he says. “Tai chi is more than old folks chasing trees.”Berry credits meditation and tai chi with helping him quit smoking. “No cigarettes for three months now,” he says.Zarita Croney, a veteran with the National Guard, says tai chi has helped her with chemical dependency. She now makes the nearly two-hour drive from Hopkinsville, Ky., to Murfreesboro each week, and has reduced her use of pills for pain.”My whole life … revolved around, ‘Oh shoot, when can I take my next pill?’ ” Croney recalls. “I’ve gone from about 90 percent of my day being on my bed to being able to come out and be social.”The VA has been aggressively trying to wean vets off high-powered opioids — using prescription data as a key measurement to judge how its hospitals across the country are doing with that goal.The VA acknowledges that there’s little evidence at this point that tai chi or mindfulness therapy or acupuncture will ease PTSD or addiction, though recently there has been research into the quality of life benefits of tai chi among the elderly.But physicians say they suspect many of the opioisa aren’t always helping veterans either, and the drugs carry more risks.Aaron Grobengieser, who oversees alternative medicine at the VA hospital in Murfreesboro, says tai chi won’t replace medication. But it might help reduce prescriptions, and the agency plans to start measuring that.”I believe this is going to be an avenue,” he says, “to really help address that group of folks [who are] looking for ways to manage those types of conditions without popping another pill.”This story is part of NPR’s reporting partnership with Nashville Public Radio and Kaiser Health News. Copyright 2018 Nashville Public Radio. To see more, visit Nashville Public Radio.
At QMSP, we have developed an International Maple Research and Innovation Network of renowned scientists dedicated to learning more about maple from Canada. Consumers love the taste of Canadian maple syrup and there is a growing body of evidence supporting the wider benefits of maple products for human health and exercise regimes.We are proud to be supporting the second Chemistry and Biological Effects of Maple Food Products Symposium at the largest gathering of the scientific community in the world.” Scientists from the University of Montreal studied cyclists for a clinical trial examining the effect of consuming maple products when exercising.It found maple water or syrup, with an equivalent carbohydrate content found in commercial sports drinks (60 g/L), can readily be used as a source of energy during endurance exercise.The study, the first maple human clinical trial, comprised 76 active males aged 18-45 during two hours of cycling immediately followed by a 20-km time trial. Supported by the Québec Maple Syrup Producers (QMSP) and Canadian Federal Government, the study also compared maple products’ sensory characteristics, including taste of maple water and diluted maple syrup during exercise, to those of a commercial sports drink. Results showed maple syrup to have less of an acidic taste than a commercial sports drink.Dr Jonathan Tremblay, Associate Professor at the University of Montreal, School of Kinesiology and Exercise Science, said: Source:https://maplescience.org/ Apr 3 2019Canadian maple syrup provides a pure energy source for endurance athletes and can help fight inflammation, according to new research published today. Using a natural product that athletes enjoy and are inclined to drink more of during exercise can be key to maintaining fluid balance. Maple syrup beverages offer an excellent alternative to commercial beverages. Sports beverages made with pure maple syrup do not contain any processed sugars, are gluten-free, vegan and free of any coloring or additives.” The study was one of several into the potential positive impact of maple products on health-related issues and exercise endurance announced at the American Chemical Society (ACS) National Meeting and Expo in Orlando, Florida.Related StoriesA short bout of exercise improves brain function, study revealsIt’s never too late to take up exercise, advise researchersRegular physical activity can be effective in reducing pain from arthritisIn a separate study, researchers discovered bioactive compounds that naturally exist in maple syrup protect the body from some negative effects linked to inflammation.A diet including foods with polyphenols, such as pure Canadian maple syrup, green tea, red wine, and fruits and vegetables may help support a healthy immune system. Inflammation is a normal part of a healthy immune response. Uncontrolled, however, inflammation can contribute to tissue damage and has been linked to several pathological conditions. There are several ways to help prevent and fight chronic inflammation, like eating foods rich in polyphenols and maintaining healthy habits such as exercise.Dr Angela Slitt, professor at University of Rhode Island, College of Pharmacy and her team found a maple syrup extract enriched with polyphenols exerts anti-inflammatory activity.Serge Beaulieu, President of Québec Maple Syrup Producers (QMSP), said:
The charity wants the Government to act on its ambition to halve childhood obesity rates by 2030 and introduce a 9 pm watershed for junk food adverts on TV and online, alongside other measures such as restricting promotional offers on unhealthy food and drinks.Professor Linda Bauld, Cancer Research UK’s prevention expert, commented: There isn’t a silver bullet to reduce obesity, but the huge fall in smoking over the years – partly thanks to advertising and environmental bans – shows that Government-led change works. It was needed to tackle sky-high smoking rates, and now the same is true for obesity.The world we live in doesn’t make it easy to be healthy and we need Government action to fix that, but people can also make changes themselves; small things like swapping junk food for healthier options and keeping active can all add up to help reduce cancer risk.” As smoking rates fall and obesity rates rise, we can clearly see the impact on a national health crisis when the Government puts policies in place – and when it puts its head in the sand.Our children could be a smoke-free generation, but we’ve hit a devastating record high for childhood obesity, and now we need urgent Government intervention to end the epidemic. They still have a chance to save lives.Scientists have so far identified that obesity causes 13 types of cancer but the mechanisms aren’t fully understood. So further research is needed to find out more about the ways extra body fat can lead to cancer.” Reviewed by James Ives, M.Psych. (Editor)Jul 3 2019New figures from Cancer Research UK show that people who are obese now outnumber people who smoke two to one in the UK, and excess weight causes more cases of certain cancers than smoking, as the charity urges Government action to tackle obesity.Almost a third of UK adults are obese and, while smoking is still the nation’s biggest preventable cause of cancer and carries a much higher risk of the disease than obesity, Cancer Research UK’s analysis revealed that being overweight or obese trumps smoking as the leading cause of four different types of cancer.Excess weight causes around 1,900 more cases of bowel cancer than smoking in the UK each year. The same worrying pattern is true of cancer in the kidneys (1,400 more cases caused by excess weight than by smoking each year in the UK), ovaries (460) and liver (180).Related StoriesLiving with advanced breast cancerResearch sheds light on sun-induced DNA damage and repairSpecial blood test may predict relapse risk for breast cancer patientsCancer Research UK launched a nationwide campaign this week to increase awareness of the link between obesity and cancer. Extra body fat sends out signals that can tell cells to divide more often and can cause damage that builds up over time and raises the risk of cancer.The campaign compares smoking and obesity to show how policy change can help people form healthier habits, not to compare tobacco with food.Michelle Mitchell, Cancer Research UK’s chief executive, said: Source:Cancer Research UK
Reviewed by James Ives, M.Psych. (Editor)Jun 29 2019Researchers at Karolinska Institutet in Sweden have found a way of using gene expression conserved across species to divide patients with the inflammatory bowel disease ulcerative colitis into two distinct groups. The findings are published in the journal Nature Communications, and the researchers hope that the method can also be used to subdivide other autoimmune diseases.Ulcerative colitis is an inflammatory bowel disease affecting the colon and rectum. It manifests itself differently in patients, and only 50 to 60 per cent respond to the treatment with so-called biological drugs.There is therefore a need to divide patients into different groups so that new pharmaceutical targets can be identified and treatments tailored accordingly.Such a grouping has now been presented by researchers at Karolinska Institutet in a study published in Nature Communications. We’ve managed to divide patients with ulcerative colitis into two molecularly distinct groups using a method that we believe can be used for other diseases too.”Study’s corresponding author Eduardo Villablanca, associate professor at the Department of Medicine, Karolinska Institutet (Solna) Related StoriesAMSBIO offers new, best-in-class CAR-T cell range for research and immunotherapyResearch sheds light on sun-induced DNA damage and repairResearch opens possibility of developing single-dose gene therapy for inherited arrhythmiasThe researchers first used openly accessible data on gene expression – transcription data – from colon biopsies from 102 patients with ulcerative colitis. But the variation between patients proved too great to break the patients down into meaningful groups.They then hit on the idea of excluding irrelevant genes in the patient material by only looking at genes whose expression is changed in both humans and mice. To do this, the group analyzed gene expressions in colon biopsies from a mouse model with ulcerative colitis. They found 57 genes in common from the mouse and patient material.Using these 57 genes, the researchers were able to identify two groups of patients, which they term UC1 and UC2. UC1 patients are characterized by the higher expression of genes involved in the recruitment of neutrophils, which are a type of immune cell. Over 87 per cent of the patients in this group also responded poorly to treatment with two of the most widely used biological drugs for ulcerative colitis. About 60 per cent of the patients in the UC2 group, however, responded to this treatment.”We demonstrate the principle that it’s possible to combine datasets from mice and humans to group previously indistinguishable patients,” says Dr Villablanca. “The results provide new knowledge on inflammatory bowel diseases and can contribute to the more tailored treatment of ulcerative colitis.” Source:Karolinska InstitutetJournal reference:Czarnewski, P. et al. (2019) Conserved transcriptomic profile between mouse and human colitis allows unsupervised patient stratification. Nature Communications. doi.org/10.1038/s41467-019-10769-x.