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August 4 2007 To continue our report from 81

first_imgAugust 4, 2007 To continue our report from 8/1/07, three individual frames have been painted and prepared to be installed in one of the door panels on the east balcony of the Crafts III building at Cafe level. [Photo & text: sa] This photo taken from the inner balcony at the top level of the Crafts III building, the Visitors Center – Gallery, gives some indication of scale of the three-level interior space and of the scale of the door panels. The panels have been installed and welding crew Philip Bonham and Darina Trendafilova fine tune placement and clip in the fly-screens. [Photo & text: sa] In past years, during the summer month, both door panels on the east and south balcony were kept open to allow a natural breeze to flow through the cafe space. Recent feedback from the health department frowned on this easy access for the fly population. To screen these giant doors presented quite a challenge and it was elegantly solved. [Photo & text: sa]last_img read more

We see the potential in gold equities as we belie

first_img We see the potential in gold equities, as we believe the price of gold is going higher, but big investors with billions of dollars to pour into an market don’t. Their money, for the most part, is still on the sidelines. This phenomenon leads us to predict that someday these institutional investors will enter this sector en masse. Once the facts sink in and the institutional world becomes convinced gold and silver prices will maintain a sustainable uptrend, they’ll be much more attracted to the equities – and just as stubborn about changing their minds once they’re on board. Now, it’s possible this group may have to be beat over the head by relentlessly  rising precious-metals prices before they enter the industry. They’ll have to believe that, say, gold hitting $1,900 again isn’t a temporary fluke but a sustainable uptrend. I don’t know what price the metal would have to maintain or how long it would have to stay there before they jump on board, but given the above chart, I think it’s safe to say they won’t be the first to the party. I personally think it will be something along the lines of what we outlined in the recent Hard Assets Alliance letter. Whenever and however it happens, though, the stampede from institutional investors into this tiny industry will be sudden and dramatic, because they tend to have a herd mentality. No one wants to be left behind. Just like they don’t want to risk buying something all their colleagues are ignoring now, they’ll rush to own the popular and exciting investment when gold stocks have their day. The consequence of this will result in dramatically higher stock prices. How high? Well, this group loves to use price models, and fair value for Newmont Mining (NEM), based on its Reserves, would be about $200/share (it’s currently trading around $44). And that’s at $1,700 gold – as the spot price rises, the value of NEM will rise exponentially, since gold would be rising faster than costs, even when inflation kicks in. That is why I’m excited about the producers. It’s the first place the institutional world will turn when gold makes a sustained move higher. Come the day those investors believe gold is about to become part of the monetary system, that bonds are no longer a safe place for money, that inflation is about to get out of control, or whatever it might be that changes their paradigm, they’ll flood into our little market and push share prices higher by an order of magnitude. When this shift gets under way, we’ll already own the stocks that institutional investors will be clamoring to buy. Maybe we should thank them now. Bank and brokerage analysts know their products, too. But when it comes to helping you make an informed decision about where the gold market is headed, they have, as Rick Rule is fond of saying, a record unblemished by success. Every year major banks and brokerage houses provide their four-year forecasts for the gold price. The following chart documents the average price projection of 25 top analysts over the past seven years, many of whom specialize in the resource industry. I might suggest pushing away from your desk so that when your jaw drops it doesn’t hit the keyboard. Common sense dictates that when you need information or advice on something you’re unfamiliar with, you consult with a professional. That’s what people do, whether refinancing a home, choosing an insurance product, or fixing a broken heater. While professionals certainly have their own agendas, they still know more about their products or services than others, and can at least help them make more informed decisions. If institutional investors are largely absent from this market, why is gold rising every year? Gold is not a trading sardine for institutions. Gold is supported by strong physical demand from individuals around the world and from central banks. Read our take here. You can see that every year since 2007, bank and brokerage analysts have as a group predicted that gold would fall, sometimes dramatically, over the next four-year period. For example, in 2007 the consensus of all estimates was that gold would decline from $656 to $523 by 2011. Instead, the price rose 140% to an average of $1,572 that year. Similarly, they predict this year that gold will fall from $1,665 to $1,515 by 2017. Even if they thought gold would move higher the first year, their best guess was that it was ultimately headed lower. So far they’ve been wrong every time. For the most part, these are analysts who do nothing but study the resource markets all day long. It’s their job. No one gets it right all the time, but this kind of track record is embarrassing. The obvious lesson is for investors to ignore price predictions from the major banks and brokerage houses – they just don’t get it. I’m sure most readers of this publication already know that. However, there’s a much bigger implication of this data that may not immediately come to mind… Why would I as a fund manager or institutional investor buy a gold stock if my analysts tell me the price of gold is going to fall? Answer: I wouldn’t. If the price of the product a company sells is expected to decline over the next few years, would you buy the company’s stock? Its earnings are almost certain to fall. As a manager of millions (or billions) of dollars, you wouldn’t buy any investment with this kind of outlook. There’s more. These same banks and brokerages have also been predicting the price of oil will rise (almost) every year. While they’ve occasionally been right about that, it means that margins for the gold producers would be expected to fall, since roughly 10% of their costs are related to fuel. So again… Why would I as a fund manager or institutional investor buy a gold stock if my analysts tell me profit margins are expected to fall? Answer: I wouldn’t. It doesn’t matter that analysts have been consistently wrong. What matters is that if the institutional world believes the gold price is likely decline and/or that margins are likely to fall, they’re not going to stick their necks out and buy gold stocks. They could lose their bonuses or even their jobs if their analyst’s predictions came true and they’d bet against them. This could be the explanation for why hedge funds, institutional investors, and other large investors haven’t entered this market en masse and could account for the disconnect between the price of gold and the trajectory of gold stocks.last_img read more

Brazil Chile Colombia Mexico

first_img Brazil Chile Colombia Mexico Peru Czech Republic Egypt Hungary Morocco Poland Russia S. Africa Turkey Europe, Middle East, Africa China India Indonesia Korea Malaysia Philippines Taiwan Thailand Asia Source: Bloomberg So, a rise in the Index implies an increase in the production of food, electricity, housing, and steel, and points to future global economic growth. As shown in the above chart, the BDI has doubled since early August and tripled year to date. A big slowdown in global economic activity doesn’t seem to be in the cards. A Good Story The facts, however, seldom present an obstacle that a good media story can’t overcome. Such was the case with the media-induced, emerging-market selloff ahead of the Fed’s anticipated “taper” announcement. The story—or at least a chapter from it—went something like this: Emerging markets are carrying big current account deficits… any twist of the Fed’s liquidity spigot will slow the flow of Western capital into emerging economies and aggravate the deficits… a rise in interest rates would ensue… higher rates will slow economic growth… better to sell emerging markets and their currencies ahead of these events. The sand in the ointment that lubricated the media jaws is that “emerging markets” is not a homogenized thing, but an array of countries with distinct economic and fiscal profiles. For a real-world perspective, let’s look at the 21 emerging markets as defined by the MSCI Market Index. Here they are, sorted by region, with countries that run a current account deficit shown in red, and those with a surplus shown in green: The skies were clear as we started final approach into Changi International Airport. Still several kilometers out in the Singapore Strait, dozens of container ships sat idle, tethered to the seabed, and seemed to stretch clear to Batam Island, part of the Indonesian archipelago. Each ship formed part of a nautical queue and waited its turn for cargo to be transshipped or offloaded at Singapore’s port terminals. Singapore is the world’s second-busiest port in terms of cargo tonnage, and number one for the transshipment of cargo. This volume of traffic and trade has turned the Singapore Strait into a major link in one of the world’s most strategic shipping lanes that connects the South China Sea with the Strait of Malacca, and all destinations west. The above anecdotal observation from my window seat aligns with recent action in the Baltic Dry Index (BDI). The BDI is an indirect measure of global supply and demand for shipping capacity. The index acts as a leading indicator in that it measures the demand for “dry” commodities (grain, coal, timber, ores) that are the raw materials used in intermediate and finished-goods manufacture. America’s Hmmm… I see a pattern here. The farther east you look, the greener it gets. It’s pretty obvious that most Asian markets were smeared as card-carrying members of the current-account-deficit club, a grossly inaccurate generalization. Indonesia, by the way, hiked interest rates in early September and revised its GDP estimate for 2013 lower to 6%, a growth rate that countries in the left and center columns of the table are yearning to achieve. Without Us, You’re Toast In 1965, Singapore, following a decade of strife to attain self-rule, became an independent nation. The thumb of British colonial occupation was lifted. The prognosis from the foreign press was immediate and unequivocal: Singapore was doomed. The only question was when. Britain had agreed to maintain its military bases in the country, the primary source of security and economic support for the fledgling country. The bases were a hundred-million-pound burden on the British treasury—closure was inevitable. A British withdrawal from Singapore was compared to the decline of the Roman Empire, where law and order collapsed as the Roman legions retreated and barbarians filled the vacuum. The latest round of emerging-market skepticism, concocted and perpetuated by an ill-informed Western media, embodies the nauseating ideal of Anglo-exceptionalism and is reminiscent of the “you can’t make it without us” conceit of the 20th century. Singapore is not an emerging market, of course, but it was, having clawed its way from backwater trading post in the hinterlands of the British Empire to today’s economic and financial powerhouse. Other Asian nations are following the path it trod, and intra-emerging-market export trends and demographics suggest that the region’s growth story is far from over.last_img read more

Free demo here

first_imgFree demo here The Turkish lira is in free fall… Two weeks ago, it announced a series of measures that it hopes will bring liquidity and support the country’s banking system. (You can read more details on these measures in this Dispatch.)Turkish President Recep Tayyip Erdoğan also asked Turkish people to get rid of their U.S. dollars and euros:If there are dollars under your pillow, take these out… immediately give these to the banks and convert to Turkish lira and, by doing this, we fight this war of independence and the future.In other words, Erdoğan wanted Turks to sell dollars to keep the lira from plunging.But many people did the exact opposite. In fact, my Turkish friend told me—at the height of the lira’s sell-off—that “all her friends were exchanging lira for dollars.”But that’s not all they were buying. I know because I was just in Turkey… We know this because trading volumes on major Turkish crypto exchanges surged during the lira’s recent crash.According to CoinMarketCap, trading volumes on BTCTurk soared 131% when the lira was falling. Paribu, another Turkish crypto exchange, saw a 108% spike in trading volume.This tells us many Turkish people took shelter in bitcoin and other cryptos. But that shouldn’t come as a surprise. I spent about three weeks in Istanbul. I also visited Turkey’s gorgeous southern coast.That was enough time for me to truly experience Turkey’s currency crisis.You see, one dollar was worth about 4.8 lira when I showed up in Turkey. Three weeks later, one dollar was worth 7 lira.This means that the lira’s value plunged 31% against the dollar in less than a month. Put another way, the dollar strengthened 46% against the lira over the same period.Now, I didn’t mind this as a tourist. Everything from meals to cab rides got cheaper by the day.But the lira’s plunge hammered everyday Turkish people, like my friend. Things got so bad that the Turkish central bank stepped in… “I don’t buy anything from Amazon anymore. I buy everything from AliExpress now. It takes two months to get here, but I save about $1.”My friend Canset told me this recently. Now, you might be wondering why she’s using AliExpress—an online retail service based in China—to purchase her everyday items.She’s doing this because the money in her wallet is losing value rapidly.You see, my friend lives in Turkey, which is in the middle of a currency crisis.Of course, you’d already know that if you have been reading the Dispatch. I wrote about the situation here and here. It’s a major story we’re following closely—and it’s another reason why you should bet on cryptocurrencies today.I’ll explain why in a moment, but first let me recap what’s happening in Turkey. Of course, Turkey isn’t the only country where desperate people have turned to bitcoin… Just click here Recommended Link Turks have been embracing cryptocurrencies for years… In fact, the market research firm Ipsos recently conducted a survey on crypto ownership across 15 countries. And it found that 18% of Turks own some form of cryptocurrency. That’s double the European average of 9%.That’s impressive. But crypto ownership in Turkey should keep rising.I say that because the same survey found that 53% of Turks believe digital currencies will be the dominant online payment method in the future. And 51% expect the value of cryptocurrencies to rise over the next year.This is a big deal. Many Turks also loaded up on cryptocurrencies… This year the lira has fallen 38% against the dollar. That’s a staggering decline. Only the Venezuelan bolívar and Sudanese pound have fared worse this year.This is why my friend is changing how she shops. If she doesn’t, she could run out of money.She’s certainly not alone, either.People all over Turkey are under pressure. You can almost feel the tension in the air. It tells me more Turks will take refuge in cryptos if the lira keeps falling… — So consider speculating on cryptos if you haven’t yet. Bitcoin is a good place to start.Just remember that bitcoin and other cryptos are extremely volatile. As always, never bet more money than you can afford to lose. And you should use stop losses and take profits as they come. Regards,Justin SpittlerBudapest, HungaryAugust 27, 2018Reader MailbagToday, we see that not everyone agrees with Doug Casey’s take on the Alex Jones ban…Doug, you have gotten completely off topic with Alex Jones. All you say, and others as well, about Jones’ content and his delivery is correct. But ask yourself this question: How did this cabal all of a sudden come together? All of a sudden the technocrats and the media in unison attacked Jones. Feel sorry for Jones… NOT! As of Monday, he was the No. 1 news app. CNN, who had held that title for years, was destroyed. Why? Because you and the public jumped on his band wagon. Jones is a gate keeper for the Israeli agenda… and where did you get this that he was somehow a 9/11 truther?You need to re-examine your information, Mr. Casey. He argues all of the time whether the narrative was wrong and Israel was a haymaker of this false flag agenda. This was not to destroy Jones, as you and others portend. It was to drive the insouciant to his site to take the alt net to its extreme. Please take a different look to see what he has been and still is. You are as dead wrong as all who have fallen for the scam of the century. —RichardAs always, if you have any questions or suggestions for the Dispatch, send them to us right here.In Case You Missed It…Have you seen these strange-looking metal poles in your city? Most people have no idea what they’re for. But in just a few short years, these towers could completely upend the entire $479 billion smartphone industry… and make well-positioned investors rich. But together they could light a serious fire under the bitcoin price. It’s also possible that bitcoin (or some other crypto) could emerge as a medium of exchange in one of these places. That would let the world know that cryptos aren’t just another speculative vehicle. They’re a legitimate threat to paper money. Relative to the dollar, the Venezuela bolívar has lost 99.99% of its value this year. The Argentine peso is down 40% on the year. The South African rand is down 12%. These are enormous declines. They’re the kind that push people to take shelter in bitcoin. NASDAQ calls it: “The biggest investment opportunity in years.” The Smart Phone Killer1000x faster, 1000x more capacity, plus the power to download a 2-and-a-half hour movie in one second. Get positioned by October 1, and you could pocket a sweet $150k profit. Of course, skeptics will be quick to point out that bitcoin hasn’t been a good store of value this year.It’s down 52% on the year versus the lira’s 38% decline. Not only that, many lesser-known cryptos are down 80% or more this year.I won’t dispute those numbers. But let’s not forget that cryptos are coming off an incredible rally.The bitcoin chart below says it all.You can see that bitcoin’s still up 2,874% over the past three years. And yes, that includes its recent crash.You’ve also got to remember that bitcoin’s been here before. You see, bitcoin has crashed 30% or more 11 other times since 2010. Each time, it bounced back stronger.You can’t say the same about the lira, which has been in steady decline. In fact, it’s lost 70% of its value against the dollar since the start of 2013. — Recommended Link Now, I’m not saying any of these countries could push bitcoin to new highs on their own… That would obviously be extremely bullish for the crypto market… President Trump Gives Order to Locate New Type of FuelRecently, President Trump signed an executive order that mandates the Interior Department to begin mapping the country to locate America’s “Brandt Oil” reserves.“Brandt Oil” is a new, clean super fuel that’s so powerful, less than two gallons worth contains enough raw energy to power your house for nine years. So it’s no surprise “Brandt Oil” applications are going mainstream.And just like any new energy revolution, early investors are minting millions. Already we’re seeing investors bag rare gains as high as 2,343%, 3,750%, and even 4,628%.To get the full story on exactly what “Brandt Oil” is – and why it’s making investors so much money right now…last_img read more

When youre thirsty a swig of fresh water brings

first_imgWhen you’re thirsty, a swig of fresh water brings instant relief. But gulp down some salty sea water and you’ll still feel parched.That’s because your brain is trying to keep the concentration of salt in your body within a very narrow range, says Zachary Knight, an associate professor in physiology at the University of California, San Francisco and an investigator with the Howard Hughes Medical Institute.”If you experience, for example, a 10 percent change, you would be very sick,” he says. “A 20 percent change and you could die.”Knight and a team of researchers wanted to know how the brain keeps that from happening. They report the results of their search in an article published Wednesday in the journal Nature.”There has to be a mechanism for the brain to track how salty the solutions that you drink are and use that to fine-tune thirst,” Knight says. “But the mechanism was unknown.”So Knight’s team began studying brain cells known as thirst neurons.First, the team piped fresh water directly into the stomachs of some thirsty mice.”Within a minute or two, infusing water into the stomach rapidly turns off these thirst neurons in the brain,” says Chris Zimmerman, a graduate student in Knight’s lab who conducted the experiment. “And not only that,” Zimmerman says, “if we give [the mouse] access to water it doesn’t drink at all.”Next the team repeated the experiment, using salty water. And this time, the thirst neurons stayed on and the animals kept searching for fresh water that would reduce the concentration of salt in their bodies.More study revealed how the system works. Cells in the gut are constantly measuring saltiness and communicating that information to thirst neurons in the brain.”What’s really exciting about this is not only that we’ve discovered this new signal from the gut to the brain, but also that we’ve found that it has a really specific role in controlling our behavior,” Zimmerman says.A second study in Nature looks at a different system that also affects salt intake.”We wanted to know how sodium appetite is regulated by the brain,” says Yuki Oka, an assistant professor of biology at Caltech and an author of the study.The first thing Oka’s team did was use a technique called optogenetics to switch on the sodium appetite neurons.The effect on mice was immediate. “They pick up a piece of rock salt and then start eating it,” Oka says.When the team switched off the sodium appetite neurons, the animals stopped eating salt.But how does this system work when there’s no scientist flipping the switch?Previous research has shown that part of the answer involves cells that measure salt concentrations in the bloodstream.But Oka’s team figured that likely wasn’t the whole answer, because animals need only a tiny amount of sodium in their diet. So they need to stop eating salt long before concentrations in blood start rising.The scientists thought there must be a second “off switch” somewhere — one that could be flipped sooner.They found it in the animals’ taste buds.”When you put sodium-salt on top of the tongue, and then, when you taste it, that’s sufficient to suppress sodium appetite neurons,” Oka says. That’s how we know to stop eating salt before we’ve consumed a harmful dose.And sports drinks, the UCSF scientists explain, contain exactly the same concentration of sodium found in our bodies; that’s how the drinks replace sodium without triggering the brain’s “stop eating salt” response. Copyright 2019 NPR. To see more, visit https://www.npr.org.last_img read more

Doctors at Wake Forest Baptist Health have develop

first_imgDoctors at Wake Forest Baptist Health have developed an iPad app that assists in colon cancer screening tests. The software puts some decision-making power into patients’ hands. It’s called mobile Patient Technology for Health – or mPATH-CRC for short. It lets patients “self-order” a colon cancer screening test while they’re in the waiting room. Colon cancer remains the second leading cause of cancer death in the U.S., but over one-third of those eligible to be screened don’t get the test.The National Cancer Institute has awarded $1.6 million in grant funds for further testing of the technology in clinics across North Carolina and Kentucky.Dr. David Miller is a professor at Wake Forest School of Medicine, and a leading researcher on the study. “What this grant funding will let us do is figure out how to get this iPad intervention — which we know works, we know it doubles the chance that people will complete colon cancer screening tests — and actually get it put into routine use in primary care practices,” says Miller.Miller also says that the mPATH-CRC application is an extension, not a replacement, for a physician’s advice.last_img read more

Testing the Open Source Waters

first_img –shares If you don’t remember to save your Write files in a .doc format, or PDF, then non-OpenOffice users who you send your files to won’t be able to read them. Learn how to successfully navigate family business dynamics and build businesses that excel. Testing the Open Source Waters Register Now » Lastly, since OpenOffice was created as a group effort and built by volunteers, its how-tos and help files are sometimes difficult to find and understand.Overall, OpenOffice provides users with a versatile office suite. Many small-business owners will find that the office suite is a gateway to the larger world of open source software. For instance, when you find that OpenOffice doesn’t offer an Outlook-like e-mail service, you might soon discover Mozilla Thunderbird, another open source program that looks and acts very much like Outlook. Soon you may begin wondering why so many thousands of your business’s hard-earned dollars went to software suites, when similar software is available for free on the internet.Donald Carroll is the founder of Calvary Copywriting in Kansas City, Missouri. Specializing in the peculiarities of small to mid-sized businesses, Donald takes pride in helping the little guys fight big competition. OpenOffice 1.2 also has a database function built in. This can be used to create bibliographies, contact lists, address books and other functions you’d expect from a relational database.Though it’s easy to learn how to use the programs–and easy on any company’s budget–OpenOffice does have some drawbacks:The database program in version 1.2 is extremely difficult to learn. I also came across compatibility issues with some of my Windows software that wouldn’t allow for the creation of databases through OpenOffice. There’s an Access-like database for OpenOffice 2.0, called Base; however, it’s still in Beta version, so some functions don’t work. And at this point, Base doesn’t have an “import” function, which many Access users find useful. It was my fault–I admit it. I was cleaning my computer’s file system, trying to speed it up a bit, when poof! My computer died. I was able to bring it back to life, but I lost a lot of programs I had to reinstall. Unfortunately, at some point during a move six months earlier, I had lost my Microsoft Office disk and now was in a bit of a jam: I was working on a project for a client, the deadline was coming up quickly, and it was too late to go to the store to buy another copy.That’s when I turned to Google. On a hunch, I searched for “Alternatives to Microsoft Office” and there I found OpenOffice.org. A quick read of OpenOffice’s website revealed a program that’s intended to be similar to Microsoft Office in look and feel, and that can read and save files in the Microsoft Office format, among others.Here’s the kicker: OpenOffice is free. Regardless of how many workstations you use the program on, it’ll never cost your company a penny. Compare that to the cost of licensing Microsoft Office Professional for just five workstations: According to a sales associate at the online retailer CDW, that’ll cost you upwards of $2,000.Being convinced–and desparate–enough to give it a try, I went through the download and install procedures, which took only a few minutes using my cable modem. I was very pleased with what I found. There’s a “Word”-like program, called Write, for drafting documents. There’s also a spreadsheet program, called Calc, that’s very similar to Excel and a presentation program called Impress that’s similar to PowerPoint. There’s also a program called Draw, which is comparable to Paint.After I became more familiar with OpenOffice, I discovered many useful features that other business owners will appreciate:Write is the OpenOffice equivalent of Word. It’s highly functional, very intuitive and has utilities for saving documents directly to PDF format, which allows for easy web publishing or portability between platforms, something Word doesn’t offer. Mail merge, table maker, object manipulation, various wizards and the ability to create your own templates are also available in Write. Next Article 4 min read Opinions expressed by Entrepreneur contributors are their own. Impress presentations can be saved directly as a Macromedia Flash file, for easy uploading to your company’s website. In PowerPoint, this can only be done by using a separate and expensive program for converting PowerPoint documents to Macromedia Flash format. Add to Queue Technology July 28, 2005 Calc is similar in almost every way to Excel, but Calc files, unlike Excel files, can be saved directly to PDF, thus saving you the time and expense of having to use a separate program–Adobe–to turn the text document into a PDF. Free Webinar | July 31: Secrets to Running a Successful Family Business Is free software really worth it? One business owner describes his first experiences with OpenOffice. Donald Carrolllast_img read more

US Charges Nine People in 30 Million Insider Trading Scheme

first_img Learn how to successfully navigate family business dynamics and build businesses that excel. Next Article U.S. Attorney for New Jersey Paul J. Fishman (2nd L) speaks during a news conference in Newark, New Jersey. –shares U.S. prosecutors have charged nine people over their alleged roles in a hacking scheme to obtain corporate press releases before they were made public, which they said generated more than $30 million of illegal trading profit.Prosecutors in Brooklyn, New York made public an insider trading indictment charging four traders: Vitaly Korchevsky, a former hedge fund manager from Glen Mills, Pennsylvania; Vladislav Khalupsky, of Brooklyn and Odessa, Ukraine and Leonid Momotok, of and Alexander Garkusha of Georgia.An separate indictment made public in New Jersey charges Ivan Turchynov and Oleksandr Ieremenko, two alleged computer hackers who live in Ukraine; Pavel Dubovoy, a trader from Ukraine; and Arkadiy Dubovoy and his son Igor Dubovoy, traders from Georgia.Authorities said that starting around February 2010, hackers infiltrated the networks of press release distributors Business Wire, MarketWired and PR Newswire, and gained access to corporate news such as financial results before it became public.According to the indictments, the news was then passed to traders who made illegal trades in stocks and options based on the stolen information, with foreign shell companies being used to share the rewards.Authorities said the scheme resulted in illegal profits on such companies as Acme Packet Inc, Align Technology Inc (ALGN.O), Caterpillar Inc (CAT.N), Dealertrack Technologies Inc (TRAK.O), Dendreon Corp, Edwards Lifesciences Corp (EW.N), Panera Bread Co (PNRA.O) and Verisign Inc (VRSN.O).Charges brought against the various defendants include securities fraud, and conspiracies to commit securities fraud, wire fraud and money laundering.A press conference to discuss the charges is scheduled for 11:30 a.m. EDT in Newark, New Jersey. A spokeswoman for the FBI said five of the defendants have been arrested.The U.S. Securities and Exchange Commission brought a related civil lawsuit charging many more defendants, and alleging that the thefts resulted in more than $100 million of illegal profit. It is seeking civil penalties and asset freezes, as well as the recoupment of illegal profits.The criminal case marks the first U.S. prosecution alleging a securities fraud scheme using hacked inside information.It is also the largest known suspected case of hacking that resulted in insider trading.None of the press release distributors or companies whose securities were traded were criminally charged. Business Wire is a unit of Warren Buffett’s Berkshire Hathaway Inc(BRKa.N).Until now, the SEC had brought only a handful of civil cases against individual hackers.In 2007, the agency filed a civil case against a Ukrainian trader named Oleksandr Dorozhko, accusing him of hacking into IMS Health Holdings Inc (IMS.N) and stealing information on earnings that he used to make profitable options trades. In 2010, a federal court ordered Dorozhko to pay $580,000.(Writing by Mica Rosenberg and Supriya Kurane; Editing by Edmund Klamann and Alden Bentley) Image credit: Reuters | Eduardo Munoz U.S. Charges Nine People in $30 Million Insider Trading Scheme Reuters August 11, 2015 3 min read Hackers This story originally appeared on Reuters Add to Queue Free Webinar | July 31: Secrets to Running a Successful Family Business Register Now »last_img read more

New mobile apps may simplify complex genomic and biome data

first_imgReviewed by James Ives, M.Psych. (Editor)Oct 10 2018Spurred by the rapidly expanding use of in-home tests for “omic” – genomic and microbiomic – data for humans, pets, and even homes themselves, university researchers have begun tackling the difficult challenge of making the results interactive and understandable to non-experts.While misinterpreting a pet’s lineage or the tracks of a cockroach across a kitchen countertop may or may not carry large financial consequences, scientific literature brims with examples of incorrect or misinterpreted omic home-test results that prompted expensive and unnecessary follow-up medical tests. Already, more than 5 million reports of genetic and microbiome (the bacteria, viruses, and fungi that live in and on our bodies) have been delivered as a result of such direct-to-consumer tests, and in some cases the emotional toll can be as consequential as the financial.Supported by a new National Science Foundation (NSF) grant, NYU Tandon School of Engineering Associate Professor Oded Nov, an expert in human-computer interaction, leads the research project with Associate Professor Orit Shaer of Wellesley College. The team is working with the Open Humans Foundation platform to fashion user studies en route to first-of-their-kind tools that he hopes industry will widely adopt.Related StoriesGrowth problems in preterm infants associated with altered gut bacteriaNew strategy may strengthen gut-brain communicationWarning issued by FDA after patient dies following fecal transplantThe team is developing mobile apps to allow users to share results and curated medical news with others within their families or a community interested in the same disease, for example. In the process, the researchers plan to design and test best practices for communicating and interacting with complex genomic and biome data.In addition, the researchers will build an UbiqOmic space to test volunteers’ understanding of data presentation and interaction tools. They will also conduct a longitudinal study in three households, whose members will self-monitor for allergens or undesired food ingredients – and perhaps discover how changing these ingredients affects their own microbiome and those of other people in the household. As part of NYU Tandon’s ITEST summer program supported by the NSF, Nov will engage New York City middle and high school students and teachers in the project.Nov, a member of the NYU Tandon faculty in the Department of Technology Management and Innovation, has long focused on human-computer interaction and social computing. He holds degrees from Tel Aviv University, the London School of Economics, and Cambridge University. His many honors include a National Science Foundation CAREER Award, as well as grants from Google, the MacArthur Foundation, and the National Academies Keck Futures Initiative.The NSF Division of Information and Intelligent Systems granted $500,000 for the research, which NYU and Wellesley College share equally.Source: http://www.poly.edu/news/new-apps-take-confusion-out-genome-and-microbiome-home-testslast_img read more

Canadian maple syrup can be used as energy source during endurance exercise

first_imgAt QMSP, we have developed an International Maple Research and Innovation Network of renowned scientists dedicated to learning more about maple from Canada. Consumers love the taste of Canadian maple syrup and there is a growing body of evidence supporting the wider benefits of maple products for human health and exercise regimes.We are proud to be supporting the second Chemistry and Biological Effects of Maple Food Products Symposium at the largest gathering of the scientific community in the world.” Scientists from the University of Montreal studied cyclists for a clinical trial examining the effect of consuming maple products when exercising.It found maple water or syrup, with an equivalent carbohydrate content found in commercial sports drinks (60 g/L), can readily be used as a source of energy during endurance exercise.The study, the first maple human clinical trial, comprised 76 active males aged 18-45 during two hours of cycling immediately followed by a 20-km time trial. Supported by the Québec Maple Syrup Producers (QMSP) and Canadian Federal Government, the study also compared maple products’ sensory characteristics, including taste of maple water and diluted maple syrup during exercise, to those of a commercial sports drink. Results showed maple syrup to have less of an acidic taste than a commercial sports drink.Dr Jonathan Tremblay, Associate Professor at the University of Montreal, School of Kinesiology and Exercise Science, said: Source:https://maplescience.org/ Apr 3 2019Canadian maple syrup provides a pure energy source for endurance athletes and can help fight inflammation, according to new research published today.center_img Using a natural product that athletes enjoy and are inclined to drink more of during exercise can be key to maintaining fluid balance. Maple syrup beverages offer an excellent alternative to commercial beverages. Sports beverages made with pure maple syrup do not contain any processed sugars, are gluten-free, vegan and free of any coloring or additives.” The study was one of several into the potential positive impact of maple products on health-related issues and exercise endurance announced at the American Chemical Society (ACS) National Meeting and Expo in Orlando, Florida.Related StoriesA short bout of exercise improves brain function, study revealsIt’s never too late to take up exercise, advise researchersRegular physical activity can be effective in reducing pain from arthritisIn a separate study, researchers discovered bioactive compounds that naturally exist in maple syrup protect the body from some negative effects linked to inflammation.A diet including foods with polyphenols, such as pure Canadian maple syrup, green tea, red wine, and fruits and vegetables may help support a healthy immune system. Inflammation is a normal part of a healthy immune response. Uncontrolled, however, inflammation can contribute to tissue damage and has been linked to several pathological conditions. There are several ways to help prevent and fight chronic inflammation, like eating foods rich in polyphenols and maintaining healthy habits such as exercise.Dr Angela Slitt, professor at University of Rhode Island, College of Pharmacy and her team found a maple syrup extract enriched with polyphenols exerts anti-inflammatory activity.Serge Beaulieu, President of Québec Maple Syrup Producers (QMSP), said:last_img read more

Students who enjoyed their alone time seem to display greater psychological health

first_img First-year students who valued and enjoyed their alone time seemed to display greater psychological health Solitary time can be useful for detaching oneself from societal pressures and getting back to one’s own values and interests, which in turn allows for better behavior regulation (with a greater sense of autonomy, choice, and self-concordance) The association between freely chosen motivation for solitude and psychological health is stronger for those who don’t feel they belong in college The findings held across two independent samples of first-year students–one at a private university in the US and one at a public university in Canada Parents play a role in shaping their children’s capacity to be alone by allowing children time for independent play. The study provides empirical evidence for the theory formulated by English pediatrician and psychoanalyst Donald Woods Winnicott in the 1950s. What do the researchers wish they had known as a green, first-year student?”I wish I had known to worry less,” says Nguyen. The transition to college can be difficult with the pressure to socialize and make new friends, she notes. However, it’s important to consider that alone time is also valuable.”At times we do want time to ourselves, to relax, so it is OK to take time for that as well,” says Nguyen.”Being alone does not make you a loner, which is a very easy stereotype to internalize when you first enter college–especially when you think that everyone around you is socializing when you are not. Solitude is a personal experience for everyone, so it is a time for you to take if you want, and just explore different ways to make it a meaningful and enjoyable experience for you.” Reviewed by James Ives, M.Psych. (Editor)Apr 10 2019Transitioning from high school to college can be stressful. Trying to fit in, making new friends, missing old ones and home, meeting professors’ and one’s own expectations–can all be daunting.The way that first-year students manage (or not) to navigate this change has long-term implications for their academic performance and ability to stick with their studies. Research has shown that one frequent pitfall during this transition period from high school to college is social isolation. Loneliness, of course, can have a serious detrimental effect on a student’s mental health, potentially leading to depression.But being alone isn’t necessarily bad, argues a team of researchers from the University of Rochester, Carleton University in Ottawa, Canada, and Ghent University in Belgium. They published their findings about the importance of me-time in the journal Motivation and Emotion.”Approaching solitude for its enjoyment and intrinsic values is linked to psychological health, especially for those who don’t feel as if they belong to their social groups,” says the study’s lead author, Thuy-vy Nguyen, who received her doctorate in psychology from the University of Rochester in 2018 and who undertook large part of the research for this study in Rochester.”These findings highlight the importance of cultivating the ability to enjoy and value solitary time as a meaningful experience, rather than trying to disregard it, or escape from it,” says Nguyen, who’ll be joining the psychology department at Durham University, England, this fall as an assistant professor.Loneliness versus alone timeWhat then marks the difference between useful and potentially detrimental solitude? The key is positive motivation, according to the researchers. A healthy, autonomous seeking of alone time is associated with greater self-esteem, a greater sense of feeling related to others, and feeling less lonely. Conversely, someone who wants to be alone because of negative social experiences will more likely experience the negative effects of solitude, such as isolation or social withdrawal. The reasons matter as they determine how we experience solitude and the benefits we can get from it, the study concludes.Nguyen is building on decades of research by her veteran Rochester mentors, Edward Deci and Richard Ryan, co-founders of self-determination theory (SDT). The theoretical framework of SDT fits nicely into the investigation of how individuals’ motivations for spending time alone contribute to well-being, the researchers note. Per definition, autonomous motivation for being alone refers to a person’s decision to spend time in solitude in a manner that is valuable and enjoyable for the person.Previous research had shown that spending too much time socializing during the first year of college–and as a result having little time for oneself–may be associated with poor adjustment.Related StoriesResearch sheds light on sun-induced DNA damage and repairWhy Mattresses Could be a Health Threat to Sleeping ChildrenPerinatal depression screenings may overlook women having suicidal ideationBut over the course of two studies, conducted with 147 first-year college students in the US (testing for self-esteem) and 223 in Canada (testing for loneliness and relatedness), the team was able to untangle the interaction between new students’ social life and their motivation for spending time alone as a predictor of their successful adjustment to college life.Nguyen says the interplay between solitary time and our social experiences has not been empirically studied before, at least not in this way.”In previous research, it has been framed in ways that those with more access to social connections tend to have a better time in solitude. But in our study, having a healthy motivation for solitude actually is associated with wellness for those who have less access to social connections,” says Nguyen.The findings in a nutshell:center_img Source:https://www.rochester.edu/newscenter/college-freshmen-need-alone-time-373042/last_img read more

Researchers find a way to divide patients with ulcerative colitis into groups

first_imgReviewed by James Ives, M.Psych. (Editor)Jun 29 2019Researchers at Karolinska Institutet in Sweden have found a way of using gene expression conserved across species to divide patients with the inflammatory bowel disease ulcerative colitis into two distinct groups. The findings are published in the journal Nature Communications, and the researchers hope that the method can also be used to subdivide other autoimmune diseases.Ulcerative colitis is an inflammatory bowel disease affecting the colon and rectum. It manifests itself differently in patients, and only 50 to 60 per cent respond to the treatment with so-called biological drugs.There is therefore a need to divide patients into different groups so that new pharmaceutical targets can be identified and treatments tailored accordingly.Such a grouping has now been presented by researchers at Karolinska Institutet in a study published in Nature Communications. We’ve managed to divide patients with ulcerative colitis into two molecularly distinct groups using a method that we believe can be used for other diseases too.”Study’s corresponding author Eduardo Villablanca, associate professor at the Department of Medicine, Karolinska Institutet (Solna) Related StoriesAMSBIO offers new, best-in-class CAR-T cell range for research and immunotherapyResearch sheds light on sun-induced DNA damage and repairResearch opens possibility of developing single-dose gene therapy for inherited arrhythmiasThe researchers first used openly accessible data on gene expression – transcription data – from colon biopsies from 102 patients with ulcerative colitis. But the variation between patients proved too great to break the patients down into meaningful groups.They then hit on the idea of excluding irrelevant genes in the patient material by only looking at genes whose expression is changed in both humans and mice. To do this, the group analyzed gene expressions in colon biopsies from a mouse model with ulcerative colitis. They found 57 genes in common from the mouse and patient material.Using these 57 genes, the researchers were able to identify two groups of patients, which they term UC1 and UC2. UC1 patients are characterized by the higher expression of genes involved in the recruitment of neutrophils, which are a type of immune cell. Over 87 per cent of the patients in this group also responded poorly to treatment with two of the most widely used biological drugs for ulcerative colitis. About 60 per cent of the patients in the UC2 group, however, responded to this treatment.”We demonstrate the principle that it’s possible to combine datasets from mice and humans to group previously indistinguishable patients,” says Dr Villablanca. “The results provide new knowledge on inflammatory bowel diseases and can contribute to the more tailored treatment of ulcerative colitis.” Source:Karolinska InstitutetJournal reference:Czarnewski, P. et al. (2019) Conserved transcriptomic profile between mouse and human colitis allows unsupervised patient stratification. Nature Communications. doi.org/10.1038/s41467-019-10769-x.last_img read more

Karnataka crisis 4 MLAs leave Renaissance hotel in Mumbai

first_img India Today Web Desk New DelhiJuly 12, 2019UPDATED: July 12, 2019 18:45 IST BC Patil (seen in centre in black shirt) was among four MLAs who left the hotel on Friday afternoon (ANI photo | File)Moments after Karnataka Chief Minister HD Kumaraswamy sought to move trust vote in the assembly, four out of 10 MLAs staying at the Renaissance hotel in Mumbai left the premises. BC Patil was among the MLAs who left the hotel.They were spotted leaving the hotel in a car towards Siddhivinayak temple. However, their destination could not be confirmed.Congress and JD (S) have issued a whip to their MLAs asking them to attend the ongoing budget session in the assembly or face action. However, the MLAs have said that the whip is not applicable as they have already resigned as legislators.But, Supreme Court has directed Speaker Ramesh Kumar to maintain status quo on the resignations tendered by 10 rebel MLAs, who had moved the court against him. The court asked the speaker not take any decision on resignation or disqualification until the court has had time to go through all the facts in the matter.Read | Why is Karnataka government always in jeopardy?Read | Karnataka crisis: CM Kumaraswamy seeks floor test, says he is ready for anythingRead | Karnataka crisis: No decision on rebel MLAs till July 16, SC tells SpeakerWatch | Karnataka crisis: Rebel MLAs return to MumbaiFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byArshi Aggarwal Next Karnataka crisis: 4 MLAs leave Renaissance hotel in MumbaiFour MLAs, including BC Patil, were spotted leaving the hotel in a car towards Siddhivinayak temple. However, their destination could not be confirmed.advertisementlast_img read more