Tag Archives: 杭州楼凤

Cancer Research UK urges Government action to tackle obesity

first_imgThe charity wants the Government to act on its ambition to halve childhood obesity rates by 2030 and introduce a 9 pm watershed for junk food adverts on TV and online, alongside other measures such as restricting promotional offers on unhealthy food and drinks.Professor Linda Bauld, Cancer Research UK’s prevention expert, commented: There isn’t a silver bullet to reduce obesity, but the huge fall in smoking over the years – partly thanks to advertising and environmental bans – shows that Government-led change works. It was needed to tackle sky-high smoking rates, and now the same is true for obesity.The world we live in doesn’t make it easy to be healthy and we need Government action to fix that, but people can also make changes themselves; small things like swapping junk food for healthier options and keeping active can all add up to help reduce cancer risk.” As smoking rates fall and obesity rates rise, we can clearly see the impact on a national health crisis when the Government puts policies in place – and when it puts its head in the sand.Our children could be a smoke-free generation, but we’ve hit a devastating record high for childhood obesity, and now we need urgent Government intervention to end the epidemic. They still have a chance to save lives.Scientists have so far identified that obesity causes 13 types of cancer but the mechanisms aren’t fully understood. So further research is needed to find out more about the ways extra body fat can lead to cancer.” Reviewed by James Ives, M.Psych. (Editor)Jul 3 2019New figures from Cancer Research UK show that people who are obese now outnumber people who smoke two to one in the UK, and excess weight causes more cases of certain cancers than smoking, as the charity urges Government action to tackle obesity.Almost a third of UK adults are obese and, while smoking is still the nation’s biggest preventable cause of cancer and carries a much higher risk of the disease than obesity, Cancer Research UK’s analysis revealed that being overweight or obese trumps smoking as the leading cause of four different types of cancer.Excess weight causes around 1,900 more cases of bowel cancer than smoking in the UK each year. The same worrying pattern is true of cancer in the kidneys (1,400 more cases caused by excess weight than by smoking each year in the UK), ovaries (460) and liver (180).Related StoriesLiving with advanced breast cancerResearch sheds light on sun-induced DNA damage and repairSpecial blood test may predict relapse risk for breast cancer patientsCancer Research UK launched a nationwide campaign this week to increase awareness of the link between obesity and cancer. Extra body fat sends out signals that can tell cells to divide more often and can cause damage that builds up over time and raises the risk of cancer.The campaign compares smoking and obesity to show how policy change can help people form healthier habits, not to compare tobacco with food.Michelle Mitchell, Cancer Research UK’s chief executive, said: Source:Cancer Research UKlast_img read more

Researchers find a way to divide patients with ulcerative colitis into groups

first_imgReviewed by James Ives, M.Psych. (Editor)Jun 29 2019Researchers at Karolinska Institutet in Sweden have found a way of using gene expression conserved across species to divide patients with the inflammatory bowel disease ulcerative colitis into two distinct groups. The findings are published in the journal Nature Communications, and the researchers hope that the method can also be used to subdivide other autoimmune diseases.Ulcerative colitis is an inflammatory bowel disease affecting the colon and rectum. It manifests itself differently in patients, and only 50 to 60 per cent respond to the treatment with so-called biological drugs.There is therefore a need to divide patients into different groups so that new pharmaceutical targets can be identified and treatments tailored accordingly.Such a grouping has now been presented by researchers at Karolinska Institutet in a study published in Nature Communications. We’ve managed to divide patients with ulcerative colitis into two molecularly distinct groups using a method that we believe can be used for other diseases too.”Study’s corresponding author Eduardo Villablanca, associate professor at the Department of Medicine, Karolinska Institutet (Solna) Related StoriesAMSBIO offers new, best-in-class CAR-T cell range for research and immunotherapyResearch sheds light on sun-induced DNA damage and repairResearch opens possibility of developing single-dose gene therapy for inherited arrhythmiasThe researchers first used openly accessible data on gene expression – transcription data – from colon biopsies from 102 patients with ulcerative colitis. But the variation between patients proved too great to break the patients down into meaningful groups.They then hit on the idea of excluding irrelevant genes in the patient material by only looking at genes whose expression is changed in both humans and mice. To do this, the group analyzed gene expressions in colon biopsies from a mouse model with ulcerative colitis. They found 57 genes in common from the mouse and patient material.Using these 57 genes, the researchers were able to identify two groups of patients, which they term UC1 and UC2. UC1 patients are characterized by the higher expression of genes involved in the recruitment of neutrophils, which are a type of immune cell. Over 87 per cent of the patients in this group also responded poorly to treatment with two of the most widely used biological drugs for ulcerative colitis. About 60 per cent of the patients in the UC2 group, however, responded to this treatment.”We demonstrate the principle that it’s possible to combine datasets from mice and humans to group previously indistinguishable patients,” says Dr Villablanca. “The results provide new knowledge on inflammatory bowel diseases and can contribute to the more tailored treatment of ulcerative colitis.” Source:Karolinska InstitutetJournal reference:Czarnewski, P. et al. (2019) Conserved transcriptomic profile between mouse and human colitis allows unsupervised patient stratification. Nature Communications. doi.org/10.1038/s41467-019-10769-x.last_img read more

Alliance Bank to undergo streamlining

first_imgTHE spotlight is on the country’s smallest lender, Alliance Bank Malaysia Bhd, which could be looking at paring down its stake in its wholly-owned subsidiary, Alliance Investment Bank Bhd (AIBB).The move, if it materialises, will come amid an extremely competitive time for the investment banking scene both here and globally where it is becoming increasingly difficult to survive without a strong niche.IPO deals have dried up in recent years not only here but regionally while other deal-making activities in Asia have had their worst start to this year since about five years ago due mostly to a global economic slowdown. A source says that advisers have already been hired to start off the process of Alliance Bank selling its majority interest in AIBB. AdChoices广告When asked, Alliance Bank neither confirmed nor denied the matter.Unlock exclusive insights, analyses, and curated news on the economy on The Star Online’s Business section with Starbiz Premium.SubscribeLog In Corporate News13 Jul 2019IJM contract termination likely due to deadline issueCorporate News13 Jul 2019Yinson continues to draw interestProperty13 Jul 2019Pioneering the wellness concept for offices in Malaysia More Stories Tags / Keywords:center_img Economy13 Jul 2019Much to benefit from Malaysia-China tiesBanking12 Jul 2019Fed’s Williams joins with other officials leaning toward rate cutsOil & Gas11 Jul 2019OPEC action and trade truce may give oil the lift it needs Corporate Newslast_img read more